Acrylamidopropyltrimonium Chloride/Acrylamide Copolymer
IARC Group 2A. Forms on high-temperature browning of starches; also a polyacrylamide impurity.
Low Tox Gear · Scanner

Is Toni & Guy Strength Plex Bond Repair Conditioner 600mL low tox? Our scanner flagged 7 ingredients (2 in the avoid tier, 5 caution) on its published label, screened against our 237 source-cited chemical rules.
IARC Group 2A. Forms on high-temperature browning of starches; also a polyacrylamide impurity.
European Society of Contact Dermatitis declared MI a "contact allergy epidemic." High allergen rates.
Documented respiratory and skin sensitiser. Common MCAS and asthma trigger.
Svanes et al. Bergen Respiratory Health Study, Am J Respir Crit Care Med 2018
Manufacturing process can leave 1,4-dioxane (probable carcinogen) and ethylene oxide as contaminants. Look for 'vacuum-stripped' products.
Common humectant. Documented contact allergen — especially for eczema-prone skin.
Chelating agent — generally tolerated but documented MCAS trigger in case reports.
Preservative — generally well-tolerated but documented as MCAS and contact-dermatitis trigger in sensitive individuals.
Each ingredient on this product's published label is matched against our 237 source-cited chemical rules, each documenting a concern from peer-reviewed research and regulatory sources. Severity tiers:
Each flag links to its primary chemical-level source, and each condition pill links to a PubMed-indexed paper that discusses the chemical class in the context of that condition. Every citation is a real peer-reviewed paper — we don't link to Wikipedia or PubMed search pages. Some pairs use a topically-broad paper (e.g. a fragrance-allergen patch-test review) rather than a single-pair study where the literature is thin. The full evidence chain (chemical → mechanism → condition → paper) is one click away.
This is automated analysis of a published label, not medical advice — always verify the label yourself before changing products. Methodology and source list at scan.lowtoxgear.com.