red
Methoxymethyl-P-Phenylenediamine
Active dye in most permanent hair colours. Severe contact allergen.
Krasteva et al. Contact Dermatitis 2009
Low Tox Gear · Scanner
Clairol Natural Instincts 2 Midnight Black Semi Permanent each
Is Clairol Natural Instincts 2 Midnight Black Semi Permanent each low tox? Our scanner flagged 13 ingredients (3 in the avoid tier, 10 caution) on its published label, screened against our 237 source-cited chemical rules.
3 avoid10 caution
13 ingredients flagged
What we flagged
red
Amino-2-Hydroxytoluene
Reproductive toxicant. Avoid during pregnancy. Common in nail polish and adhesives.
red
Methylchloroisothiazolinone
European Society of Contact Dermatitis declared MI a "contact allergy epidemic." High allergen rates.
amber
Propylene Glycol
Common humectant. Documented contact allergen — especially for eczema-prone skin.
amber
Sodium Sulfite
Documented MCAS, asthma and migraine trigger in sensitive individuals.
amber
P-Aminophenol
PPD-family hair-dye intermediate.
amber
Steareth-200
Manufacturing process can leave 1,4-dioxane (probable carcinogen) and ethylene oxide as contaminants. Look for 'vacuum-stripped' products.
amber
Methylresorcinol
Hair-dye coupler with thyroid-disrupting activity in animal studies.
Full ingredients (from label)
Colour Enhancing Crme Ingredients: Aqua/Water/EauPropylene GlycolEthanolamineCetearyl AlcoholTrisodium Ethylenediamine DisuccinateCitric AcidParfum/FragranceSodium SulfiteDicetyl Phosphate2-Methoxymethyl-p-PhenylenediamineAscorbic AcidCeteth-10 Phosphatep-AminophenolSteareth-2002-MethylresorcinolXanthan GumResorcinolSodium HydroxideTitanium Dioxide / (CI 77891)m-AminophenolDisodium EDTA4-Amino-2-HydroxytolueneTocopheryl Acetate.Colour Activator Ingredients: Aqua/Water/EauParaffinum Liquidum/ Mineral Oil/ Huile mineraleHydrogen PeroxideCetearyl AlcoholSodium Cetearyl SulfateSalicylic AcidPhosphoric AcidDisodium PhosphateDisodium PyrophosphateSodium StannateEtidronic Acid.Brilliant Shine Conditioner Ingredients: Aqua/Water/EauBis-Hydroxy/Methoxy AmodimethiconeStearyl AlcoholCetyl AlcoholStearamidopropyl DimethylamineGlutamic AcidParfum/FragranceBenzyl AlcoholCitric AcidBenzyl BenzoateEDTAHistidineCocos Nucifera (Coconut) OilSodium ChlorideHexyl CinnamalLinaloolMagnesium NitrateTrimethylsiloxysilicateAloe Barbadensis Leaf JuiceMethylchloroisothiazolinoneMagnesium ChlorideMethylisothiazolinoneBHTAscorbic AcidPotassium SorbateSodium BenzoateSodium Sulfite.
How this analysis is generated
Each ingredient on this product's published label is matched against our 237 source-cited chemical rules, each documenting a concern from peer-reviewed research and regulatory sources. Severity tiers:
- Avoid (red) — banned or restricted in the EU, UK or Canada but still legal in the US, IARC-listed, or strong contact-allergen evidence.
- Caution (amber) — regulatory caution, contamination risk, or condition-specific irritant.
- Mild (green) — low concern but commonly avoided in low-tox formulations.
Each flag links to its primary chemical-level source, and each condition pill links to a PubMed-indexed paper that discusses the chemical class in the context of that condition. Every citation is a real peer-reviewed paper — we don't link to Wikipedia or PubMed search pages. Some pairs use a topically-broad paper (e.g. a fragrance-allergen patch-test review) rather than a single-pair study where the literature is thin. The full evidence chain (chemical → mechanism → condition → paper) is one click away.
This is automated analysis of a published label, not medical advice — always verify the label yourself before changing products. Methodology and source list at scan.lowtoxgear.com.