Methoxymethyl-P-Phenylenediamine
Active dye in most permanent hair colours. Severe contact allergen.
Krasteva et al. Contact Dermatitis 2009
Low Tox Gear · Scanner

Is Clairol Natural Instincts Hair Colour 3 Brown Black Semi Permanent each low tox? Our scanner flagged 9 ingredients (2 in the avoid tier, 7 caution) on its published label, screened against our 237 source-cited chemical rules.
Active dye in most permanent hair colours. Severe contact allergen.
Krasteva et al. Contact Dermatitis 2009
Reproductive toxicant. Avoid during pregnancy. Common in nail polish and adhesives.
Common humectant. Documented contact allergen — especially for eczema-prone skin.
Hair-dye coupler with thyroid-disrupting activity in animal studies.
Documented MCAS, asthma and migraine trigger in sensitive individuals.
Manufacturing process can leave 1,4-dioxane (probable carcinogen) and ethylene oxide as contaminants. Look for 'vacuum-stripped' products.
PPD-family hair-dye intermediate.
Banned as a food additive in the EU (2022) due to nano-particle genotoxicity concerns. Inhalation classified IARC Group 2B.
Each ingredient on this product's published label is matched against our 237 source-cited chemical rules, each documenting a concern from peer-reviewed research and regulatory sources. Severity tiers:
Each flag links to its primary chemical-level source, and each condition pill links to a PubMed-indexed paper that discusses the chemical class in the context of that condition. Every citation is a real peer-reviewed paper — we don't link to Wikipedia or PubMed search pages. Some pairs use a topically-broad paper (e.g. a fragrance-allergen patch-test review) rather than a single-pair study where the literature is thin. The full evidence chain (chemical → mechanism → condition → paper) is one click away.
This is automated analysis of a published label, not medical advice — always verify the label yourself before changing products. Methodology and source list at scan.lowtoxgear.com.