amber
Disodium EDTA
Chelating agent — generally tolerated but documented MCAS trigger in case reports.
Low Tox Gear · Scanner
Unknown
Is Avène Unknown low tox? Our scanner flagged 2 ingredients (2 in the caution tier) on its published label, screened against our 237 source-cited chemical rules.
2 caution
2 ingredients flagged
What we flagged
amber
Sodium Benzoate
Implicated in childhood hyperactivity studies and reported MCAS trigger.
Full ingredients (from label)
AVENE THERMAL SPRING WATER AVENE AQUAL C12-15 ALKYL BENZOATE-COCO CARIMATE ENCI NANOJ DISOPROPYL ADIPATE WATER AQUAL BISETHHERVICMPHENOL METHO NONE FOUNGINCERY-2 DIPOLYHYDROXYSTEARATE GLYCERINBUTYL METHOXYDIBENZOMA GICOL CAPIMIC/CAPRIC TRIGLYCERIDE. CAPRYLYL GLYCOL DISODIUM EDTA HEIANTHUS ANNU ANNUS SEED OIL HYDROXYCAPRIC ACID. LAURYL GLUCOSIDE OKOTHAZOLDINE COL SODIUM BENZOATESODIUM CITRATE. SODIUM LAURYL GLUCOSE CARBOMATE TOCOPHEROL TOCOPHERYL GLUCOSIDE XANTHAN GUM
How this analysis is generated
Each ingredient on this product's published label is matched against our 237 source-cited chemical rules, each documenting a concern from peer-reviewed research and regulatory sources. Severity tiers:
- Avoid (red) — banned or restricted in the EU, UK or Canada but still legal in the US, IARC-listed, or strong contact-allergen evidence.
- Caution (amber) — regulatory caution, contamination risk, or condition-specific irritant.
- Mild (green) — low concern but commonly avoided in low-tox formulations.
Each flag links to its primary chemical-level source, and each condition pill links to a PubMed-indexed paper that discusses the chemical class in the context of that condition. Every citation is a real peer-reviewed paper — we don't link to Wikipedia or PubMed search pages. Some pairs use a topically-broad paper (e.g. a fragrance-allergen patch-test review) rather than a single-pair study where the literature is thin. The full evidence chain (chemical → mechanism → condition → paper) is one click away.
This is automated analysis of a published label, not medical advice — always verify the label yourself before changing products. Methodology and source list at scan.lowtoxgear.com.